Physician Education
Advanced Fellowships in Inflammatory Bowel Disease (IBD) at Mount Sinai Hospital
The Advanced Fellowship in Inflammatory Bowel Disease is a one year, funded position which will provide the applicant with focused training in clinical care and clinical/translational or basic research in Inflammatory Bowel Disease. The Fellowship will be based primarily at Mount Sinai Hospital in Toronto, Canada.
The program will be designed according to the interests of the successful applicant, with the approval of the Faculty. The intent of the Fellowship is to position the trainee for a fulltime academic appointment by providing the skills necessary to achieve a university faculty position if desired. It would also be useful for a community practice position with a strong interest in the clinical care of IBD patients.
To learn more about the Advanced Fellowship in Inflammatory Bowel Disease and how to apply, download the brochure (1 mb pdf)
Publications in IBD
Dassopoulos T, Nguyen GC, Bitton A,
Bromfield GP, Schumm LP, Wu Y, Elkadri A, Regueiro M, Siemanowski B,
Torres EA, Gregory FJ, Kane SV, Harrell LE, Franchimont D, Achkar JP,
Griffiths A, Brant SR, Rioux JD, Taylor KD, Duerr RH, Silverberg MS, Cho
JH, Steinhart AH. Assessment of reliability and validity of IBD
phenotyping within the National Institutes of Diabetes and Digestive and
Kidney Diseases (NIDDK) IBD Genetics Consortium (IBDGC). Inflammatory
Bowel Diseases 2007; 13(8):975-983.
De Jager PL, Franchimont D,
Waliszewska A, Bitton A, Cohen A, Langelier D, Belaiche J, Vermeire S,
Farwell L, Goris A, Libioulle C, Jani N, Dassopoulos T, Bromfield GP,
Dubois B, Cho JH, Brant SR, Duerr RH, Yang H, Rotter JI, Silverberg MS,
Steinhart AH, Daly MJ, Podolsky DK, Louis E, Hafler DA, Rioux JD; Quebec
IBD Genetics Consortium; NIDDK IBD Genetics Consortium. The role of the
Toll receptor pathway in susceptibility to inflammatory bowel diseases.
Genes Immun. 2007 Jul;8(5):387-97. Epub 2007 May 31.
Elkadri A,
Lal S, Stempak JM, Walters T, Griffiths AM, Greenberg GR, Steinhart AH,
Silverberg MS. Increasing prevalence of serological markers predicts
aggressive Crohn’s disease behaviour. Gastroenterology 2007; 132 (4):
A362.
Hugot JP, Zaccaria I, Cavanaugh J, Yang H, Vermeire S,
Lappalainen M, Schreiber S, Annese V, Jewell DP, Fowler EV, Brant SR,
Silverberg MS, Cho J, Rioux JD, Satsangi J, Parkes M for the IBD
International Genetics Consortium. Prevalence of CARD15/NOD2 mutations
in Caucasian healthy people. American Journal of Gastroenterology 2007;
102(6):1259-1267.
Kennedy ED, To T, Steinhart AH, Detsky A,
Llewellyn-Thomas HA, McLeod RS. Do patients consider postoperative
maintenance therapy for Crohn's disease worthwhile? Inflamm Bowel Dis.
2007 Oct 11; [Epub ahead of print]
Lal S, Steinhart AH.
Infliximab for ulcerative colitis following liver transplantation. Eur J
Gastroenterol Hepatol 2007; 19:277-280.
Lal S, Steinhart AH. Diphyllobothrium latum: a case of an incidental finding. World J Gastroenterol. 2007 Mar 28;13(12):1875-6.
Lal S, Appelton J, Mascarenhas J, Stempak JM, Esplen MJ, Silverberg MS.
Attitudes toward genetic testing in patients with inflammatory bowel
disease. European Journal of Gastroenterology and Hepatology 2007;
19(4):321-327.
Maunder RG, Greenberg GR, Lancee WJ, Steinhart
AH, Silverberg MS. The impact of ulcerative colitis is greater in
unmarried and young patients. Can J Gastroenterol. 2007
Nov;21(11):715-20.
Muise AM, Walters T, Wine E, Griffiths AM,
Turner D, Duerr RH, Regueiro MD, Ngan BY, Xu W, Sherman PM, Silverberg
MS, Rotin D. Protein-tyrosine phosphatase sigma is associated with
ulcerative colitis. Current Biology 2007; 17(14):1212-1218.
Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A, Green
T, Kuballa P, Barmada MM, Datta LW, Shugart YY, Griffiths AM, Targan
SR, Ippoliti AF, Bernard EJ Mei L, Nicolae DL, Regueiro M, Schumm LP,
Steinhart AH, Rotter JI, Duerr RH, Cho JH, Daly MJ, Brant SR.
Genome-wide association study identifies five susceptibility loci for
Crohn's disease and implicates a role for autophagy in disease
pathogenesis. Nature Genetics 2007; 39: 596-604. [Epub 2007 Apr 15]
Silverberg MS, Duerr RH, Brant SR, Bromfield G, Datta LW, Jani N, Kane
SV, Rotter JI, Schumm LP, Steinhart AH, Taylor KD, Yang H, Cho JH, Rioux
JD, Daly MJ for the NIDDK IBD Genetics Consortium. Refined genomic
localization and ethnic differences observed for the IBD5 association
with Crohn’s disease. European Journal of Human Genetics 2007;
15(3):328-335.
Steinhart AH, Forbes A, Mills EC, Rodgers-Gray
BS, Travis SP. Systematic review: the potential influence of mesalazine
formulation on maintenance of remission in Crohn's disease. Aliment
Pharmacol Ther. 2007 Jun 15;25(12):1389-99.
Turner D, Steinhart
AH, Griffiths AM. Omega 3 fatty acids (fish oil) for maintenance of
remission in ulcerative colitis. Cochrane Database of Systematic Reviews
2007 Issue 3. Art. No. CD006443; DOI: 10.1002/14651858.CD006443.pub2.
Turner D, Otley AR, Mack D, Hyams J, de Bruijne J, Uusoue K, Walters
TD, Zachos M, Mamula P, Beaton DE, Steinhart AH, Griffiths AM.
Development, validation, and evaluation of a pediatric ulcerative
colitis activity index: a prospective multicenter study.
Gastroenterology. 2007 Aug;133(2):423-32. Epub 2007 May 21.
Turner D, Walsh CM, Benchimol EI, Mann EH, Thomas KE, Chow C, McLernon
RA, Walters TD, Steinhart AH, Griffiths AM. Severe paediatric ulcerative
colitis: incidence, outcomes, and optimal timing for second line
therapy. Gut. 2007 Nov 2; [Epub ahead of print]
2006
Achkar JP, Dassopoulos T, Silverberg MS, Tuvlin JA, Duerr RH, Brant
SR, Siminovitch K, Reddy D, Datta LW, Bayless TM, Zhang L, Barmada MM,
Rioux JD, Steinhart AH, McLeod RS, Griffiths AM, Cohen Z, Yang H,
Bromfield GP, Schumm P, Hanauer SB, Cho JH, Nicolae DL.
Phenotype-stratified genetic linkage study demonstrates that IBD2 is an
extensive ulcerative colitis locus. American Journal of Gastroenterology
2006; 101(3): 572-580.
Duerr RH, Taylor KD, Brant SR, Rioux
JD, Silverberg MS, Daly MJ, Steinhart AH, Abraham C, Regueiro M,
Griffiths A, Dassopoulos T, Bitton A, Yang H, Targan S, Datta LW,
Kistner EO, Schumm LP, Lee A, Gregersen PK, Barmada MM, Rotter JI,
Nicolae DL, Cho JH. A genome-wide association study identified IL23R as
an inflammatory bowel disease gene. Science 2006;314:1461-3.
[e-published Science Express 10/26/2006]
Lal S, Stempak JM,
Elkadri AA, Law C, Walters TD, Griffiths AM, Greenberg GR, Steinhart AH,
Silverberg MS. Novel association between the C3435T polymorphism of the
MDR1 gene and Crohn’s disease. Gastroenterology 2006; 130(4): A5584.
Lal S, Stempak JM, Law C, Elkadri AA, Steinhart AH, Silverberg MS.
Association between the C3435T polymorphism of the MDR1 gene and
Crohn’s disease. Inflamm Bowel Dis 2006;12:1006-7.
Lal S, Steinhart AH. Antibiotic therapy for Crohn’s disease. Can J Gastroenterol 2006;20:651-5.
Maser EA, Villella R, Silverberg MS, Greenberg GR. Association of
trough serum infliximab to clinical outcome after scheduled maintenance
treatment for Crohn's disease. Clinical Gastroenterology and Hepatology
2006; 4:1248-1254.
Maunder RG, Lancee WJ, Hunter JJ, Greenberg
GR, Steinhart AH. Attachment insecurity moderates the relationship
between disease activity and depressive symptoms in ulcerative colitis.
Inflamm Bowel Dis 2005;11(10):919-26
Maunder RG, Greenberg GR,
Nolan RP, Lancee WJ, Steinhart AH, Hunter JJ. Pattern of autonomic
response to acute stress predicts disease activity in ulcerative
colitis. Eur J Gastroenterol Hepatol 2006;18:413-20.
Maunder RG,
Greenberg GR, Hunter JJ, Lancee WJ, Steinhart AH, Silverberg MS.
Psychobiological subtypes of ulcerative colitis: pANCA status moderates
the relationship between disease activity and psychological distress.
American Journal of Gastroenterology 2006; 101(11):2546-2551.
Nguyen GC, Torres EA, Regueiro M, Bromfield G, Bitton A, Stempak J,
Dassopoulos T, Schumm P, Gregory FJ, Griffiths AM, Hanauer SB, Hanson J,
Harris ML, Kane SV, Orkwis HK, Lahaie R, Oliva-Hemker M, Pare P, Wild
GE, Rioux JD, Yang H, Duerr RH, Cho JH, Steinhart AH, Brant SR,
Silverberg MS. Inflammatory bowel disease characteristics among African
Americans, Hispanics, and non-Hispanic Whites: characterization of a
large North American cohort. Am J Gastroenterol. 2006
May;101(5):1012-23.
Regueiro M, Loftus EV, Steinhart AH, Cohen
RD. Medical management of left-sided ulcerative colitis and proctitis.
Critical evaluation of therapeutic trials. Inflamm Bowel Dis 2006;12:
979-994.
Regueiro M, Loftus EV, Steinhart AH, Cohen RD. Clinical
guidelines for the medical management of left-sided ulcerative colitis
and proctitis. Summary statement. Inflamm Bowel Dis 2006; 12: 972-978.
Satsangi J, Silverberg MS, Vermeire S, Colombel JF. Leading Article:
The Montreal classification of inflammatory bowel disease:
controversies, consensus, and implications. Gut 2006; 55: 749-753.
Silverberg MS. OCTNs: Will the real IBD5 gene please stand up. World Journal of Gastroenterology 2006; 12 (23): 3678-3681.
Turner D, Walsh C, Steinhart AH, Griffiths AM. Response to
corticosteroids in severe ulcerative colitis: a systematic review of the
literature and meta-regression. Clin Gastroenterol Hepatol 2007; 5:
103-110 [epub 2006 Dec 8].
Van Bodegraven AA, Curley CR, Hunt
KA, Monsuur AJ, Linskens RK, Onnie CM, Crusius JB, Annese V, Latiano A,
Silverberg MS, Bitton A, Fisher SA, Steinhart AH, Forbes A, Sanderson J,
Prescott NJ, Strachan DP, Playford RJ, Mathew CG, Wijmenga C, Daly MJ,
Rioux JD, Van Heel DA. Genetic Variation in Myosin IXB Is Associated
With Ulcerative Colitis. Gastroenterology. 2006;131:1768-74.[Epub 2006
Sept 8]
Walters TD, Silverberg MS. Genetics of inflammatory
bowel disease: current status and future directions. Canadian Journal of
Gastroenterology 2006; 20(10): 633-639.
Xue S, Stempak JM,
Elkadri AA, Greenberg GR, Walters TD, Griffiths AM, Steinhart AH,
Silverberg MS. Serological markers are associated with severity of
disease and need of surgery in IBD patients. Gastroenterology 2006;
130(4): A197.
2005
Feagan BG, Greenberg GR, Wild G, Fedorak RN, Pare P, McDonald JWD,
Dube R, Cohen A, Steinhart AH, Landau S, Aguzzi RA, Fox IH, Vandervoort
MK. Treatment of ulcerative colitis with a humanized antibody to the
alpha-4 beta-7 integrin. N Engl J Med 2005; 352:2499-507.
Marcelletti J, Moskovitz D, Stempak J, Steinhart AH, Greenberg GR, Cohen
Z, McLeod RS, Simpson L, Smith K, Wang S, Carroll S, Silverberg MS.
Anti-microbial antibody markers as prognostic indicators of inflammatory
bowel disease course. Gastroenterology 2005; 128(4): A305.
Otley A, Steinhart AH. Budesonide for induction of remission in Crohn's
disease. Cochrane Database Syst Rev. 2005: CD000296. Review.
Pierik M, Yang H, Barmada MM, Cavanaugh JA, Annese V, Brant SR, Cho JH,
Duerr RH, Hugot JP, McGovern DP, Paavola-Sakki P, Radford-Smith GL,
Pavli P, Silverberg MS, Schreiber S, Taylor KD, Vlietinck R and the IBD
International Genetics Consortium. The IBD international genetics
consortium provides further evidence for linkage to IBD4 and shows
gene-environment interaction. Inflammatory Bowel Diseases 2005;11(1):
1-7.
Sands BE, Abreu MT, Ferry GD, Griffiths AM, Hanauer SB,
Isaacs KL, Lewis JD, Sandborn WJ, Steinhart AH. Design Issues and
Outcomes in IBD Clinical Trials. Inflamm Bowel Dis 2005;11:S22-8.
Siffledeen JS, Fedorak RN, Siminoski K, Jen H, Vaudan E, Abraham N,
Steinhart H, Greenberg G. Randomized trial of etidronate plus calcium
and vitamin D for treatment of low bone mineral density in Crohn’s
disease. Clin Gastroenterol Hepatol 2005;3:122-32.
Silverberg
MS, Brant SR, Torres E, Regueiro M, Achkar JP, Duerr RH, Cho JH, Rioux
JD, Bromfield FP, Yang H, Steinhart AH. Characterization of a large
repository for the study of inflammatory bowel disease genetics.
Gastroenterology 2005; 128(4): A137.
Silverberg MS, Cho JH,
Duerr RH, Bromfield GP, Brant SR, Yang H, Rioux JD, Daly MJ. Association
of the IBD5 locus with inflammatory bowel disease in a very large North
American population. Gastroenterology 2005; 128(4): A137.
Silverberg MS, Satsangi J, Ahmad T, Arnott ID, Bernstein CN, Brant SR,
Caprilli R, Colombel JF, Gasche C, Geboes K, Jewell DP, Karban A, Loftus
Jr EV, Pena AS, Riddell RH, Sachar DB, Schreiber S, Steinhart AH,
Targan SR, Vermeire S, Warren BF. Toward an integrated clinical,
molecular and serological classification of inflammatory bowel disease:
Report of a Working Party of the 2005 Montreal World Congress of
Gastroenterology. Canadian Journal of Gastroenterology 2005; 19 Suppl
A:5-36.
Silverberg MS. The time has come for NOD2/CARD15
testing for families with Crohn's disease: pro. Inflammatory Bowel
Diseases 2005; 11(5): 504-506.
2004
Appelton JI, Mascarenhas J, Esplen MJ, Butler K, Rubin DT, Silverberg
MS. Demand for genetic testing for inflammatory bowel disease.
Gastroenterology 2004; 126(4):A352.
Karban AS, Okzaki T,
Panhuysen CIM, Gallegos T, Potter JJ, Bailey-Wilson JE, Silverberg MS,
Duerr RH, Cho JH, Gregersen PK, Wu Y, Achkar JP, Dassopoulos T, Mezey E,
Bayless TM, Nouvet FJ, Brant SR. Functional annotation of a novel NFKB1
promoter polymorphism that increases risk for ulcerative colitis. Human
Molecular Genetics 2004;13(1):35-45.
Kennedy ED, Urbach DR,
Krahn MD, Steinhart AH, Cohen Z, McLeod RS. Azathioprine or ileocolic
resection for steroid-dependent terminal ileal Crohn's disease? A Markov
analysis. Dis Colon Rectum 2004;47:2120-30.
Mow WS, Landers CJ,
Steinhart AH, Feagan BG, Croitoru K, Seidman E, Greenberg GR, Targan
SR. High-level serum antibodies to bacterial antigens are associated
with antibiotic-induced clinical remission in Crohn’s disease: a pilot
study. Dig Dis Sci. 2004 Aug; 49(7-8):1280-6.
Newman B,
Silverberg MS, Gu X, Zhang Q, Lazaro A, Steinhart AH, Greenberg GR,
Griffiths AM, McLeod RS, Cohen Z, Fernandez-Vina M, Amos CI, Siminovitch
K. CARD15 and HLA DRB1 alleles influence susceptibility and disease
localization in Crohn's disease. American Journal of Gastroenterology
2004; 99(2): 306-315.
Panaccione R, Fedorak RN, Aumais G,
Bernstein CN, Bitton A, Croitoru K, Enns R, Feagan B, Fishman M,
Greenberg G, Griffiths A, Marshall JK, Rasul I, Sadowski D, Seidman E,
Steinhart H, Sutherland L, Walli E, Wild G, Williams CN, Zachos M;
Canadian Association of Gastroenterology. Canadian Association of
Gastroenterology Clinical Practice Guidelines: the use of infliximab in
Crohn’s disease. Can J Gastroenterol. 2004 Aug;18(8):503-8.
Siffledeen JS, Fedorak RN, Siminoski K, Jen H, Vaudan E, Abraham N,
Steinhart H, Greenberg G. Bones and Crohn’s: risk factors associated
with low bone mineral density in patients with Crohn’s disease. Inflamm
Bowel Dis 2004 May;10(3):220-8.
Steinhart AH. Commentary: Bone density in women with inflammatory bowel disease. Can J Gastroenterol. 2004 Mar;18(3):183-4.
van Heel DA, Fisher SA, Kirby A, Daly MJ, Rioux JD, Lewis CM and the
Genome Scan Meta-Analysis Group of the IBD International Genetics
Consortium (Silverberg MS, contributing author). Inflammatory bowel
disease susceptibility loci defined by genome scan meta-analysis of 1952
affected relative pairs. Human Molecular Genetics 2004;13 (7):
763-770.
2003
Aghdassi E, Wendland BE, Steinhart AH, Wolman SL, Jeejeebhoy K,
Allard JP. Antioxidant vitamin supplementation in Crohn's disease
decreases oxidative stress. a randomized controlled trial. Am J
Gastroenterol. 2003 Feb;98:348-53.
Evans JP, Steinhart AH, Cohen
Z, McLeod RS. Home total parenteral nutrition: an alternative to early
surgery for complicated inflammatory bowel disease. J Gastrointest Surg.
2003 May-Jun;7(4):562-6.
Griffiths AM, Sherman P, Thijs G, Ray
P, Silverberg MS. Prevalence of NOD2/CARD15 mutations in pediatric IBD.
Gastroenterology 2003; 124(4):A367.
Nikolaus S, Rutgeerts P,
Fedorak R, Steinhart AH, Wild GE, Theuer D, Mohrle J, Schreiber S.
Interferon beta-1a in ulcerative colitis: a placebo-controlled,
randomised, dose escalating study. Gut. 2003 Sep;52(9):1286-90. Erratum
in: Gut. 2003 Nov;52(11)1657.
Siffledeen JS, Siminoski K,
Steinhart H, Greenberg G, Fedorak RN. The frequency of vitamin D
deficiency in adults with Crohn’s disease. Can J Gastroenterol 2003
Aug;17(8):473-8.
Silverberg MS, Berk T, Riddell R, Gallinger S.
Significance of fundic gland polyp carpeting in familial adenomatous
polyposis. Gastroenterology 2003; 124(4):A549.
Silverberg MS,
Mirea L, Bull SB, Murphy JE, Steinhart AH, Greenberg GR, McLeod RS,
Cohen Z, Wade JA, Siminovitch KA. A population and family-based study
of Canadian families reveals association of HLA DRB1*0103 with colonic
involvement in inflammatory bowel disease. Inflammatory Bowel Diseases
2003;9(1):1-9.
2002
Bernstein CN, Eaden J, Steinhart AH, Munkholm P, Gordon PH. Cancer
prevention in inflammatory bowel disease and the chemoprophylactic
potential of 5-aminosalicylic acid. Inflamm Bowel Dis. 2002
Sep;8(5):356-61. Review.
Habtezion A, Silverberg MS, Parkes R,
Mikolainis S, Steinhart AH. Risk factors for low bone density in Crohn’s
disease. Inflamm Bowel Dis. 2002 Mar;8(2):87-92.
Mirea L, Bull
SB, Silverberg MS, Siminovitch KA. Case study in data analysis: The
genetic analysis of inflammatory bowel disease. The Canadian Journal of
Statistics 2002; 30(1): 137-145.
Moskovitz D, Steinhart H, Amre
D, McLeod R, Siminovitch K, Cohen Z, Greenberg G, Seidman E, Silverberg
MS. Prevalence of serological markers in familial inflammatory bowel
disease. Gastroenterology 2002;122(4):A176.
Silverberg MS, Mirea
L, Bull SB, Murphy JE, Steinhart H, Greenberg GR, McLeod RS, Cohen Z,
Wade JA, Siminovitch KA. A population and family-based study of Canadian
families reveals association of HLA DRB1*0103 with colonic involvement
in inflammatory bowel disease. Gastroenterology 2002;122(4):A299.
Steinhart AH, Feagan BG, Greenberg GR, Wong CJ, Vandervoort M,
Mikolainis S, Croitoru K, Seidman E, Leddin DJ, Bitton A, Drouin E,
Cohen A, Greenberg GR. Combined budesonide and antibiotic therapy for
active Crohn’s disease: a randomized controlled trial. Gastroenterology.
2002 Jul;123(1):33-40.
2001
de Rooy E.C., Toner B.B., Maunder, R.G., Greenberg G.R., Baron D.,
Steinhart A.H., McLeod R., Cohen Z., Concerns of patients with
inflammatory bowel disease: results from a clinical population. Am J
Gastroenterol, 96 (6), 2001, 1816-1821.
Feagan BG, Steinhart AH,
Wild G, Fedorak F, Pare P, Enns R, Panaccione R. Infliximab in the
treatment of Crohn's disease: efficacy, safety, and pharmacoeconomics.
Canadian Journal of Pharmacology, (8)4 2001, 188-198
Hunter J.,
Maunder R.G. Using attachment theory to understand illness behavior.
General Hospital Psychiatry, (4), 2001, 177-182.
Maunder R.G.,
Hunter J.J., Attachment and psychosomatic medicine: Developmental
contributions to stress and disease. Psychosom Med, 63 (4), 2001,
556-567.
Maunder R., Esplen MJ Supportive-expressive group
psychotherapy for inflammatory bowel disease. Canadian Journal of
Psychiatry, (7), September 2001, 622-626.
Rioux JD, Daly MJ,
Silverberg MS, Lindblad K, Steinhart AH, Cohen Z, Delmonte T, Kocher K,
Miller K, Guschwan S, Kulbokas EJ, O'Leary S, Winchester E, Dewar K,
Green T, Stone V, Chow C, Cohen A, Langelier D, Lapointe G, Gaudet D,
FaithJ, Branco N, Bull SB, McLeod RS, Griffiths AM, Bitton A, Greenberg
GR, LanderES, Siminovitch KA, Hudson TJ. Genetic variation in the 5q31
cytokine gene cluster confers susceptibility to Crohn disease. Nature
Genetics. 2001 Oct; 29(2):223-8.
Silverberg MS, Boright A,
Siminovitch KA. Positional cloning and disease gene identification. In:
Kalow W, Meyer UA, Tyndale R, eds. Pharmacogenomics. New York: Marcel
Dekker, 2001, pp 363-387.
Silverberg MS, Clelland C, Murphy JE,
Steinhart AH, McLeod RS, Greenberg GR,Cohen Z, Siminovitch KA. Carrier
rate of APC I1307K is not increased in inflammatory bowel disease
patients of Ashkenazi Jewish origin. Human Genetics. 2001
Mar;108(3):205-10.
Silverberg MS, Moskovitz DN, Daly MJ, Rioux
JD, McLeod RS, Greenberg GR, Cohen Z, Hudson TJ, Siminovitch KA.
Steinhart AH. Diagnostic misclassification reduces the ability to detect
linkage in inflammatory bowel disease genetic studies. Gut
2001;6:773-776.
Simms L, Steinhart AH. Budesonide for
maintenance of remission in Crohn's disease (Cochrane Review). Cochrane
Database System Rev. 2001;1:CD002913.
Steinhart AH. Clinical perspectives – biologics in IBD: What’s all the fuss? Can J Gastroenterol. 2001 Dec;15(12):799-804.
Wendland BE, Aghdassi E, Tam C, Carrrier J, Steinhart AH, Wolman SL,
Baron D,Allard JP. Lipid peroxidation and plasma antioxidant
micronutrients in Crohn disease. American Journal of Clinical Nutrition.
2001 Aug;74(2):259-64.
The IBD International Genetics
Consortium (Silverberg MS, one of the authors). International
collaboration provides convincing linkage replication in complex disease
through analysis of a large pooled dataset: Crohn's disease and
chromosome 16. American Journal of Human Genetics 2001;68:1165-1171.
2000
Casati, J., Toner, B.B., de Rooy, E., Drossman, D., Maunder, R.
Concerns of patients with inflammatory bowel disease: A review of
emerging themes. Dig Dis Sci, 45 (1), 2000, 26-31.
Feagan BG,
Fedorak RN, Irvine EJ, Wild G, Sutherland L, Steinhart AH, Greenberg GR,
Koval J, Wong CJ, Hopkins M, Hanauer SB, McDonald JWD. A comparison of
methotrexate with placebo for the maintenance of remission in Crohn's
disease. New England Journal of Medicine 2000;342:1627-32
Kennedy ED, Detsky AS, Llewellyn-Thomas HA, O'Connor BI, Varkul M,
Steinhart AH, Cohen Z, McLeod RS. Can the standard gamble be used to
determine utilities for uncertain health states? An example using
post-operative maintenance therapy in Crohn's disease. Medical Decision
Making 2000; 20:72-78.
MacRae HM, Regehr G, Leadbetter W,
Reznick RK: A Comprehensive Assessment of Senior Surgical Residents.
American Journal of Surgery 2000: 179-3: pp 190-3.
Maunder R.G.,
Mediators of stress effects in inflammatory bowel disease: Not the
usual suspects, Journal of Psychosomatic Research, 48, 2000, 569-77.
Maunder R., Lancee, W., Greenberg, G., Hunter, J., Fernandes, B.
Insecure attachment in a subgroup of ulcerative colitis defined by ANCA
status. Dig Dis Sci, 45, 2000, 2127-2132.
Maunder, R.
Psychotherapy for inflammatory bowel disease: New prospects, in Trends
in Inflammatory Bowel Disease Therapy 1999, C.N. Williams, R.F. Bursey,
D.G. Gall et al. (eds.) Kluwer Academic Publishers, Boston, 2000.
Moskovitz, D.N., Maunder R.G., Cohen, Z., McLeod, R.S., MacRae, H.
Coping behavior and social support contribute independently to higher
quality of life after surgery for inflammatory bowel disease. Dis Colon
Rectum, 43 (4), 2000, 517-21.
Moskovitz DN, Maunder RG, Cohen Z,
mcLeod RS, MacRae H: Use of community resources before inflammatory
bowel disease surgery is associated with postsurgical quality of life.
Canadian Journal of Gastroenterology 2000: 14(2): pp 95-8.
Rioux
JD, Silverberg MS, Daly MJ, Steinhart AH, McLeod RS, Griffiths AM,
Green T, Grettin TS, Stone V, Bull SB, Bitton A, Williams CN, Greenberg
GR, Cohen Z, Lander ES, Hudson TJ, Siminovitch KA. Genome-wide search in
Canadian families with inflammatory bowel disease reveals two novel
susceptibility loci. American Journal of Human Genetics
2000;66:1863-1870.
Rioux JD, Silverberg MS, Daly MJ, Steinhart
AH, McLeod RS, Griffiths AM, Green T, Brettin TS, Stone V, Bull SB,
Bitton A, Williams CN, Greenberg GR, Cohen Z, Lander ES, Hudson TJ,
Siminovitch KA. Genomewide search in Canadian families with inflammatory
bowel disease reveals two novel susceptibility loci. American Journal
of Human Genetics 2000; 66:1863-1870.
Silverberg MS, Daly MJ,
Rioux JD, McLeod RS, Greenberg GR, Cohen Z, Lander ES, Hudson T,
Siminovitch KA, Steinhart AH. Effect of diagnostic misclassification on
the ability to detect linkage in inflammatory bowel disease.
Gastroenterology 2000;118(4):A337.
Silverberg MS, Somani AK,
Siminovitch KA. Genetics of inflammatory bowel disease: where are we?
In: Williams CN, Bursey RF, Gall DG, Martin F, McLeod RS, Sutherland LR,
Wallace JL, eds. Trends in Inflammatory Bowel Disease Therapy 1999.
Dordrecht, The Netherlands: Kluwer Academic Publishers, 2000:3-12.
Silverberg MS, Steinhart AH. Bone density in inflammatory bowel
disease. Clinical Perspectives in Gastroenterology 2000;3(3):117-124.
Silverberg MS, Steinhart AH, Siminovitch KA, Cole DEC, Rubin LA,
Greenberg GR. Genetic and environmental factors associated with
diminished bone mineral density differ in ulcerative colitis and Crohn’s
disease. Gastroenterology 2001;120(5):A457.
Steinhart AH. Maintenance therapy in Crohn's disease. Canadian Journal of Gastroenterology. 2000 Sep;14 Suppl C:23C-28C.
Steinhart AH. Topic: Clinical Perspective - Biologics in IBD: What's
all the fuss? Canadian Journal of Gastroenterology 2000 (In press).
Steinhart AH. Use of corticosteroids in inflammatory bowel disease:
Canadian Association of Gastroenterology Practice Guidelines. Canadian
Journal of Gastroenterology 2000 (in press).
Szalay D, Macrae H,
Regher G, Reznick R: Using operative outcome to assess technical skill.
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