Professional Publications 2001
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Rioux JD, Daly M.J, Silverberg MS, Lindblad K, Steinhart H, Cohen Z, Delmonte T, Kocher K, Miller K, Guschwan S, Kulbokas EJ, O'Leary S, Winchester E, Dewar K, Green T, Stone V, Chow C, Cohen A, Langelier D, Lapointe G, Gaudet D, Faith J, Branco N, Bull SB, McLeod RS, Griffiths AM, Bitton A, Greenberg GR, Lander ES, Siminovitch KA, Hudson TJ. Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn's disease. Nature Genetics 2001:29:223-228. PubMed PMID: 11586304.
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Silverberg MS, Clelland C, Murphy JE, Steinhart AH, McLeod RS, Greenberg GR, Cohen Z, Siminovitch KA.Carrier rate of APC I1307K is not increased in inflammatory bowel disease patients of Ashkenazi Jewish origin. Human Genetics 2001;108(3):205-210. PubMed PMID: 11354631.
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Silverberg MS, Moskovitz DN, Daly MJ, Rioux JD, McLeod RS, Greenberg GR, Cohen Z, Hudson TJ, Siminovitch KA. Steinhart AH. Diagnostic misclassification reduces the ability to detect linkage in inflammatory bowel disease genetic studies. Gut. 2001:6:773-776. PubMed PMID: 11709510.
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The IBD International Genetics Consortium (Silverberg MS, one of the authors). International collaboration provides convincing linkage replication in complex disease through analysis of a large pooled dataset: Crohn's disease and chromosome 16. American Journal of Human Genetics .2001:68:1165-1171. PubMed PMID: 11309682.
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Hemming AW, Gallinger S, Greig PD, Cattral MS, Langer B, Taylor BR, Verjee Z. Giesbrecht E, Nakamachi Y, Furuya KN. The hippurate ratio as an indicator of functional hepatic reserve for resection of hepatocellular carcinoma in cirrhotic patients. Journal of Gastrointestinal Surgery. 2001:5:316-321. PubMed PMID: 11360056
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Lal G, Gallinger S: Genetics of Pancreatic Cancer: What are the Risks? Review Article In: Canadian Journal of CME, 2001:13:pp 191-209.
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Gryfe R, Gallinger S. Microsatellite instability, mismatch repair deficiency, and colorectal cancer. Surgery. 2001:130:17-20.
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Temple LK, McLeod RS, Gallinger S, Wright JG. Essays on science and society: defining disease in the genomics era. Science. 2001:293:807-808. PubMed PMID: 11486074.
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Lal G, Ash C, Hay K, Redston M, Kwong E, Hancock B, Mak T, Kargman S, Evans JF, Gallinger S: Suppression of intestinal polyps in Msh2-deficient and Non-Msh2-deficient multiple intestinal neoplasia mice by a specific cyclooxygenase-2 inhibitor and by a dual cyclooxygenase-1/2 inhibitor. Cancer Research 2001 61:pp 6131-6136. PubMed PMID: 11507063.
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Esplen MJ, Madlensky L, Butler K, McKinnon W, Bapat B, Wong J, Aronson M, Gallinger S. Motivations and psychosocial impact of genetic testing for HNPCC. American Journal of Medical Genetics. 2001:103:9-15. PubMed PMID: 11562928.
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Levy I, Greig PD, Gallinger S, Langer B, Sherman M. Resection of hepatocellular carcinoma without preoperative tumor biopsy. Annals of Surgery. 2001:234:206-209. PubMed PMID: 11505066.
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Poritz LS, Blackstein M, Berk T, Gallinger S, McLeod RS, Cohen Z. Extended follow-up of patients treated with cytotoxic chemotherapy for intra-abdominal desmoid tumor. Diseases of the Colon & Rectum. 2001:44:1268-1273. PubMed PMID: 11584198.
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Marotta A, Tan C, Gray V, Malik S, Gallinger S, Sanghera J, Dupuis B, Owen D, Dedhar S, Salh B. Dysregulation of integrin-linked kinase (ILK) signaling in colonic polyposis. Oncogene. 2001:20:6250-6257. PubMed PMID: 11593435.
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Maunder RG, Esplen MJ. Supportive-expressive group psychotherapy for persons with inflammatory bowel disease. Canadian Journal of Psychiatry - Revue Canadienne de Psychiatrie. 2001:46:622-626. PubMed PMID: 11582823.